(19)
(11) EP 1 104 294 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
23.11.2005 Bulletin 2005/47

(45) Mention of the grant of the patent:
28.09.2005 Bulletin 2005/39

(21) Application number: 99933947.6

(22) Date of filing: 13.07.1999
(51) International Patent Classification (IPC)7: A61K 31/07, A61K 31/595
(86) International application number:
PCT/US1999/015769
(87) International publication number:
WO 2000/003700 (27.01.2000 Gazette 2000/04)

(54)

COMPOSITIONS AND METHODS OF TREATING ABNORMAL CELL PROLIFERATION

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON ABNORMALER ZELLVERMEHRUNG

COMPOSITIONS ET PROCEDES DE TRAITEMENT D'UNE PROLIFERATION CELLULAIRE ANORMALE

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 16.07.1998 US 116632

(43) Date of publication of application:
06.06.2001 Bulletin 2001/23

(73) Proprietor: LEO PHARMA A/S
2750 Ballerup (DK)

(72) Inventor:
  • ACHKAR, Charles C.
    North Bergen, NJ 07047 (US)

(74) Representative: Volmer, Johannes Cornelis et al
Exter Polak & Charlouis B.V., P.O. Box 3241
2280 GE Rijswijk
2280 GE Rijswijk (NL)


(56) References cited: : 
EP-A- 0 512 814
WO-A-84/02845
US-A- 4 866 048
US-A- 5 547 947
 EP-A- 0 579 915
WO-A-96/40154
US-A- 5 514 672
   
  • DATABASE EMBASE ON STN 9710995 SKOPINSKA ET AL: 'Calcitriol and isotretinoin combined therapy for precancerous and cancerous skin lesions' & JOURNAL OF DERMATOLOGICAL TREATMENT 01 August 1997, pages 5 - 10
  • DIXON H.B.F.: 'Nomenclature of retinoids' PURE AND APPLIED CHEMISTRY vol. 55, no. 4, 1983, OXFORD, GB, pages 721 - 726, XP001182901
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).