(19)
(11) EP 1 104 309 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
05.07.2006 Bulletin 2006/27

(45) Mention of the grant of the patent:
03.05.2006 Bulletin 2006/18

(21) Application number: 99939113.9

(22) Date of filing: 10.08.1999
(51) International Patent Classification (IPC): 
A61K 48/00(2006.01)
C12N 15/87(2006.01)
(86) International application number:
PCT/US1999/018064
(87) International publication number:
WO 2000/009086 (24.02.2000 Gazette 2000/08)

(54)

CO-LYOPHILIZED COMPLEX COMPRISING A NUCLEIC ACID VECTOR AND A FORMULATING AGENT

CO-LYOPHILISIERTER KOMPLEX UMFASSEND EINEN NUKLEINSÄUREVEKTOR UND EIN FORMULIERUNGSAGENS

COMPLEXE CO-LYOPHILISE COMPRENANT UN VECTEUR D'ACIDE NUCLEIQUE ET UN AGENT DE FORMULATION


(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 14.08.1998 US 96572 P

(43) Date of publication of application:
06.06.2001 Bulletin 2001/23

(73) Proprietor: Valentis Inc.
Burlingame, CA 94010 (US)

(72) Inventors:
  • BRUNO, Maria
    The Woodlands, TX 77381 (US)
  • TAGLIAFERRI, Jenna
    Houston, TX 77098 (US)
  • LAWSON, Luke
    Spring, TX 77386 (US)
  • LOGAN, Mark, J.
    The Woodlands, TX 77381 (US)
  • MUMPER, Russ
    The Woodlands, TX 77381 (US)

(74) Representative: Harrison Goddard Foote 
40-43 Chancery Lane
London WC2A 1JA
London WC2A 1JA (GB)


(56) References cited: : 
WO-A-93/00807
WO-A-96/24664
WO-A-96/41873
WO-A-96/21470
WO-A-96/34109
   
  • ED: BUDAVARI ET AL: "THE MERCK INDEX, TWELFTH EDITION" 1996 , MERCK & CO., INC. , WHITEHOUSE STATION, NJ XP002130975 entry 1086 page 177
  • ED: BUDAVARI ET AL: "THE MERCK INDEX, TWELFTH EDITION" 1996 , MERCK & CO., INC. , WHITEHOUSE STATION, NJ XP002130976 entry 867 page 139 -page 140
  • RUSSELL J MUMPER ET AL: "Polyvinyl derivatives as novel interactive polymers for controlled Gene delivery to muscle" PHARMACEUTICAL RESEARCH,US,NEW YORK, NY, vol. 13, no. 5, May 1996 (1996-05), pages 701-709-709, XP002118167 ISSN: 0724-8741
  • MUMPER R J ET AL: "Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle" JOURNAL OF CONTROLLED RELEASE,NL,ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, vol. 52, no. 1-2, 2 March 1998 (1998-03-02), pages 191-203, XP004113667 ISSN: 0168-3659
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).