(19)

(11)

EP 1 104 486 A1

(12)

(43) Date of publication: 06.06.2001 Bulletin 2001/23 (21) Application number: 99935685.0 (22) Date of filing: 19.07.1999

(51) International Patent Classification (IPC)7: C12Q 1/58, C12P 19/34, C07H 21/04 (86) International application number: PCT/US9916/247 (87) International publication number: WO 0008/206 (17.02.2000 Gazette 2000/07)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 04.08.1998 US 95233 P (71) Applicant: Diadexus LLC Santa Clara, CA 95054 (US)	(72) Inventors: YANG, Fei Sunnyvale, CA 94086 (US) SUN, Yongming San Jose, CA 95128 (US) RECIPON, Herve San Francisco, CA 94115 (US) MACINA, Roberto, A. San Jose, CA 95136 (US) (74) Representative: Suèr, Steven Johannes et al Ablett & Stebbing,Caparo House,101-103 Baker Street London W1M 1FD London W1M 1FD (GB)