(19)

(11)

EP 1 105 118 A1

(12)

(43) Date of publication: 13.06.2001 Bulletin 2001/24 (21) Application number: 98961766.7 (22) Date of filing: 19.11.1998

(51) International Patent Classification (IPC)7: A61K 31/335, C07D 305/14 (86) International application number: PCT/US9824/997 (87) International publication number: WO 9925/334 (27.05.1999 Gazette 1999/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 19.11.1997 US 974404 (71) Applicant: Xechem, Inc. New Brunswick, NJ 08901 (US)	(72) Inventors: PANDEY, Ramesh, C. Highland Park, NJ 08904 (US) YANKOV, Luben, K. Edison, NJ 08817 (US) (74) Representative: Hirsch, Peter, Dipl.-Ing. et al Klunker Schmitt-Nilson HirschWinzererstrasse 106 80797 München 80797 München (DE)