(19)
(11) EP 1 105 140 A2

(12)

(88) Date of publication A3:
24.08.2000

(43) Date of publication:
13.06.2001 Bulletin 2001/24

(21) Application number: 99937019.0

(22) Date of filing: 11.08.1999
(51) International Patent Classification (IPC)7A61K 31/67, A61P 19/08, A61P 19/10, A61P 25/00, A61P 25/28
(86) International application number:
PCT/JP9904/338
(87) International publication number:
WO 0009/100 (24.02.2000 Gazette 2000/08)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 12.08.1998 JP 22830098

(71) Applicant: Takeda Chemical Industries, Ltd.
Osaka-shi,Osaka 541-0045 (JP)

(72) Inventors:
  • MAKINO, Haruhiko
    Kawabe-gunHyogo 666-0251 (JP)
  • FUJISAWA, Yukio
    Tsukuba-shiIbaraki 305-0032 (JP)
  • HAZAMA, Masatoshi
    Ikeda-shiOsaka 563-0029 (JP)
  • SOHDA, Takashi
    Takatsuki-shiOsaka 569-0002 (JP)

(74) Representative: Best, Michael, Dr. et al
Lederer, Keller & RiedererPatentanwältePrinzregentenstrasse 16
80538 München
80538 München (DE)

   


(54) BENZOTHIEPINE COMPOUNDS AS ENHANCER OF CELL DIFFERENTIATION INDUCTION FACTOR