TREATMENT OF TUMORS WITH OLIGONUCLEOTIDES DIRECTED TO INSULIN-LIKE GROWTH FACTOR-I RECEPTOR - Patent 1105150

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EP 1 105 150 A1

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(43)	Date of publication:
	13.06.2001 Bulletin 2001/24

(21)	Application number: 99941078.0

(22)	Date of filing: 13.08.1999

(51)	International Patent Classification (IPC)⁷: A61K 38/10, A61P 35/00, A61K 48/00, C12N 15/11, C12P 19/34

(86)	International application number:
	PCT/US9918/306

(87)	International publication number:
	WO 0009/145 (24.02.2000 Gazette 2000/08)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

13.08.1998 US 96354 P
24.12.1998 US 113599 P

(71)	Applicant: THOMAS JEFFERSON UNIVERSITY
	PhiladelphiaPennsylvania 19107 (US)

(72)	Inventors:
	ANDREWS, David, W. Philadelphia, PA 19115 (US) BASERGA, Renato, L. Ardmore, PA 19115 (US) RESNICOFF, Mariana Philadelphia, PA 19102 (US) ABRAHAM, David Wynnewood, PA 19096 (US)

(74)	Representative: Hallybone, Huw George et al
	CARPMAELS AND RANSFORD43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

(54)	TREATMENT OF TUMORS WITH OLIGONUCLEOTIDES DIRECTED TO INSULIN-LIKE GROWTH FACTOR-I RECEPTOR