(19)
(11) EP 1 105 412 A1

(12)

(43) Date of publication:
13.06.2001 Bulletin 2001/24

(21) Application number: 98942211.8

(22) Date of filing: 17.08.1998
(51) International Patent Classification (IPC)7C07K 5/06, A61K 38/55
(86) International application number:
PCT/US9817/449
(87) International publication number:
WO 0009/542 (24.02.2000 Gazette 2000/08)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(71) Applicant: CORTECH, INC.
Denver, CO 80221 (US)

(72) Inventors:
  • GYORKOS, Albert, C.
    Westminster, CO 80234 (US)
  • SPRUCE, Lyle, W.
    Chula Vista, CA 91910 (US)
  • LEIMER, Axel, H.
    Lakewood, CO 80227 (US)
  • CHERONIS, John, C.
    Conifer, CO 80433 (US)

(74) Representative: Mallalieu, Catherine Louise et al
D. Young & Co.,21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)

   


(54) SERINE PROTEASE INHIBITORS COMPRISING ALPHA-KETO HETEROCYCLES