(19)

(11)

EP 1 105 526 A1

(12)

(43) Date of publication: 13.06.2001 Bulletin 2001/24 (21) Application number: 00936474.6 (22) Date of filing: 02.06.2000

(51) International Patent Classification (IPC)7: C12Q 1/68, C12Q 1/70, C12N 5/10 (86) International application number: PCT/US0015/313 (87) International publication number: WO 0075/376 (14.12.2000 Gazette 2000/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 03.06.1999 US 137531 P (71) Applicant: THOMAS JEFFERSON UNIVERSITY Philadelphia,Pennsylvania 19107 (US)	(72) Inventor: FEITELSON, Mark, A. North Wales, PA 19454 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)