(19)
(11) EP 1 109 796 A1

(12)

(43) Date of publication:
27.06.2001 Bulletin 2001/26

(21) Application number: 00950282.4

(22) Date of filing: 30.06.2000
(51) International Patent Classification (IPC)7: C07D 277/34, C07D 277/36, C07D 417/06, C07D 417/10, C07D 513/04, A61K 31/425, A61K 31/44
(86) International application number:
PCT/US0018/211
(87) International publication number:
WO 0102/377 (11.01.2001 Gazette 2001/02)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 01.07.1999 US 142173 P
01.07.1999 JP 18761699
28.10.1999 JP 30757699

(71) Applicants:
  • Geron Corporation
    Menlo Park, CA 94025 (US)
  • KYOWA HAKKO KOGYO CO., LTD.
    Chiyoda-ku,Tokyo 100-8185 (JP)

(72) Inventors:
  • CHIN, Allison, C.
     (US)
  • HOLCOMB, Ryan
     (US)
  • PIATYSZEK, Mieczyslaw, A.
     (US)
  • SINGH, Upinder
     (US)
  • TOLMAN, Richard, L.
     (US)
  • AKAMA, Tsutomu
     (US)
  • KANDA, Yutaka
     (JP)
  • ASAI, Akira
     (JP)
  • YAMASHITA, Yoshinori
     (JP)
  • ENDO, Kaori
     (JP)
  • YAMAGUCHI, Hiroyuki
     (JP)

(74) Representative: Bassil, Nicholas Charles et al
Kilburn & Strode20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) TELOMERASE INHIBITORS AND METHODS OF THEIR USE