(19)

(11)

EP 1 112 377 A1

(12)

(43) Date of publication: 04.07.2001 Bulletin 2001/27 (21) Application number: 99930522.0 (22) Date of filing: 22.06.1999

(51) International Patent Classification (IPC)7: C12Q 1/68, G01N 33/53, C12N 11/00, C12M 1/00, C07H 21/04 (86) International application number: PCT/US9914/029 (87) International publication number: WO 9967/423 (29.12.1999 Gazette 1999/52)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 22.06.1998 US 90266 P (71) Applicant: The Regents of the University of California Oakland, CA 94607-5200 (US)	(72) Inventors: CHARYCH, Deborah, H. Albany, CA 94706 (US) JONAS, Ulrich,Max-Planck-Ins.für Polymerforschung 55128 Mainz (DE) (74) Representative: Glawe, Delfs, Moll & Partner  PatentanwälteRothenbaumchaussee 58 20148 Hamburg 20148 Hamburg (DE)