(19)

(11)

EP 1 113 786 A1

(12)

(43) Date of publication: 11.07.2001 Bulletin 2001/28 (21) Application number: 99964928.8 (22) Date of filing: 22.12.1999

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 9/20, A61K 9/22 (86) International application number: PCT/SE9902/474 (87) International publication number: WO 0105/376 (25.01.2001 Gazette 2001/04)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 20.07.1999 SE 9902742 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventors: EKLUND, Marianne S-433 70 Sävedalen (SE) LÖFROTH, Jan-Erik S-431 83 Mölndal (SE) SUNDGREN, Mats S-431 83 Mölndal (SE)