| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
| (30) |
Priority: |
17.09.1998 JP 26355098
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| (43) |
Date of publication of application: |
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11.07.2001 Bulletin 2001/28 |
| (73) |
Proprietor: Otsuka Pharmaceutical Co., Ltd. |
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Tokyo 101-8535 (JP) |
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| (72) |
Inventors: |
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- HORIE, Masato
Naruto-shi, Tokushima 772-0051 (JP)
- OKUTOMI, Keiichi c/o OTSUKA PHARMACEUTICAL CO.LTD.
Tokushima 771-0192 (JP)
- TANIGUCHI, Yoshihiro
Tokushima-shi,
Tokushima 771-0125 (JP)
- SUZUKI, Mikio c/o OTSUKA PHARMACEUTICAL CO.LTD.
Tokushima 771-0192 (JP)
- OHBUCHI, Yutaka
Tokushima-shi,
Tokushima 771-0130 (JP)
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| (74) |
Representative: HOFFMANN EITLE |
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Patent- und Rechtsanwälte
Arabellastrasse 4
81925 München
81925 München (DE) |
| (56) |
References cited: :
WO-A-97/18224
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JP-A- 3 048 696
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- DATABASE EMBL EBI; 31 August 1995 (1995-08-31) FUJIWARA T. ET AL.: "Human fetal brain
cDNA 5'-end GEN-425G08" retrieved from EBI Database accession no. D61641 XP002291885
- BRAKENHOFF R H ET AL: "THE HUMAN E48 ANTIGEN, HIGHLY HOMOLOGOUS TO THE MURINE LY-6
ANTIGEN THB, IS A GPI-ANCHORED MOLECULE APPARENTLY INVOLVED IN KERATINOCYTE CELL-CELL
ADHESION" JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, NEW YORK, US, US,
vol. 129, no. 6, 1 June 1995 (1995-06-01), pages 1677-1689, XP000563620 ISSN: 0021-9525
- MAO M ET AL: "RIG-E, A HUMAN HOMOLOG OF THE MURINE LY-6 FAMILY, IS INDUCED BY RETINOIC
ACID DURING THE DIFFERENTIATION OF ACUTE PROMYELOCYTIC LEUKEMIA CELL" PROCEEDINGS
OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON,
US, vol. 93, no. 12, 11 June 1996 (1996-06-11), pages 5910-5914, XP002044081 ISSN:
0027-8424
- CRAY C ET AL: "Regulation and selective expression of Ly-6A/E, a lymphocyte activation
molecule, in the central nervous system." BRAIN RESEARCH. MOLECULAR BRAIN RESEARCH.
JUN 1990, vol. 8, no. 1, June 1990 (1990-06), pages 9-15, XP002291818 ISSN: 0169-328X
- HORIE M. ET AL.: 'Isolation and Chararacterization of New Member of the Human Ly6
Gene Family (LY6H)' GENOMICS vol. 53, November 1998, pages 365 - 368, XP002932440
- FLEMING T.J. ET AL.: 'Characterization of Two Novel Ly-6 Genes' J. IMMUNOL. vol. 150,
no. 12, 1993, pages 5379 - 5390, XP002932441
- FRIEDMAN S. ET AL.: 'Analysis of three distinct Ly6-A-related cDNA sequences isolated
from rat kidney' IMMUNOGENETICS vol. 31, no. 2, 1990, pages 104 - 111, XP002932442
- GRAUBERT T. ET AL.: 'Characterization of the murine and human Ly-6 gene clusters'
BLOOD vol. 90, no. 1, 1997, page 145B, PART 2, NR. 3363, XP002932443
- NOSTEN-BERTRAND M. ET AL.: 'Normal spatial learning despite regional inhibition of
LTP in mice lacking Thy-1' NATURE vol. 379, 1996, pages 826 - 829, XP002932444
- GUMLEY T.P. ET AL.: 'Tissue expression structure and function of the murine Ly-6 family
of molecules' IMMUNOL. AND CELL. BIOL. vol. 73, no. 4, 1995, pages 277 - 296, XP002932445
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