ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY................................JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/0The file contains technical information submitted after the application was filed and not included in this specification200708301114861CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120081001W172deBibliographieenBibliographyfrBibliographieEP99943357.6199909162001032820050301jaenen2635509819980917JP2008100120084020010711200128200611292006482006061320081001200840C12N 15/12 20060101AFI20040819BHEP C12N 15/63 20060101ALI20040819BHEP C12N 5/10 20060101ALI20040819BHEP C07K 14/705 20060101ALI20040819BHEP C07K 16/28 20060101ALI20040819BHEP C12Q 1/68 20060101ALI20040819BHEP A61K 38/17 20060101ALI20040819BHEP A61K 48/00 20060101ALI20040819BHEP G01N 33/68 20060101ALI20040819BHEP deLY6H-GENenLY6H GENEfrGENE LY6HWO-A-97/18224JP-A- 3 048 696DATABASE EMBL EBI; 31 August 1995 (1995-08-31) FUJIWARA T. ET AL.: "Human fetal brain cDNA 5'-end GEN-425G08" retrieved from EBI Database accession no. D61641 XP002291885BRAKENHOFF R H ET AL: "THE HUMAN E48 ANTIGEN, HIGHLY HOMOLOGOUS TO THE MURINE LY-6 ANTIGEN THB, IS A GPI-ANCHORED MOLECULE APPARENTLY INVOLVED IN KERATINOCYTE CELL-CELL ADHESION" JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, NEW YORK, US, US, vol. 129, no. 6, 1 June 1995 (1995-06-01), pages 1677-1689, XP000563620 ISSN: 0021-9525MAO M ET AL: "RIG-E, A HUMAN HOMOLOG OF THE MURINE LY-6 FAMILY, IS INDUCED BY RETINOIC ACID DURING THE DIFFERENTIATION OF ACUTE PROMYELOCYTIC LEUKEMIA CELL" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 12, 11 June 1996 (1996-06-11), pages 5910-5914, XP002044081 ISSN: 0027-8424CRAY C ET AL: "Regulation and selective expression of Ly-6A/E, a lymphocyte activation molecule, in the central nervous system." BRAIN RESEARCH. MOLECULAR BRAIN RESEARCH. JUN 1990, vol. 8, no. 1, June 1990 (1990-06), pages 9-15, XP002291818 ISSN: 0169-328XHORIE M. ET AL.: 'Isolation and Chararacterization of New Member of the Human Ly6 Gene Family (LY6H)' GENOMICS vol. 53, November 1998, pages 365 - 368, XP002932440FLEMING T.J. ET AL.: 'Characterization of Two Novel Ly-6 Genes' J. IMMUNOL. vol. 150, no. 12, 1993, pages 5379 - 5390, XP002932441FRIEDMAN S. ET AL.: 'Analysis of three distinct Ly6-A-related cDNA sequences isolated from rat kidney' IMMUNOGENETICS vol. 31, no. 2, 1990, pages 104 - 111, XP002932442GRAUBERT T. ET AL.: 'Characterization of the murine and human Ly-6 gene clusters' BLOOD vol. 90, no. 1, 1997, page 145B, PART 2, NR. 3363, XP002932443NOSTEN-BERTRAND M. ET AL.: 'Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1' NATURE vol. 379, 1996, pages 826 - 829, XP002932444GUMLEY T.P. ET AL.: 'Tissue expression structure and function of the murine Ly-6 family of molecules' IMMUNOL. AND CELL. BIOL. vol. 73, no. 4, 1995, pages 277 - 296, XP00293244520040901HORIE, Masato261, Aza Minami, Takashima, Naruto-choNaruto-shi, Tokushima 772-0051JPOKUTOMI, Keiichi c/o OTSUKA PHARMACEUTICAL CO.LTD.463-10, Kagasuno, Kawauchi-choTokushima 771-0192JPTANIGUCHI, YoshihiroRafore II 706, 5-1, Kanaoka, Kawauchi-choTokushima-shi, Tokushima 771-0125JPSUZUKI, Mikio c/o OTSUKA PHARMACEUTICAL CO.LTD.463-10, Kagasuno, Kawauchi-choTokushima 771-0192JPOHBUCHI, YutakaImagireryo, 463-30, Kagasuno, Kawauchi-choTokushima-shi, Tokushima 771-0130JPOtsuka Pharmaceutical Co., Ltd.0763160086 665 A/FI2-9, Kanda-Tsukasamachi, Chiyoda-kuTokyo 101-8535JPHOFFMANN EITLE00101511Patent- und Rechtsanwälte Arabellastrasse 481925 MünchenDEATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSEJP199900503919990916jaWO20000173452000033020001320010711200128