(19)
(11) EP 1 115 718 A1

(12)

(43) Date of publication:
18.07.2001 Bulletin 2001/29

(21) Application number: 99944814.5

(22) Date of filing: 24.09.1999
(51) International Patent Classification (IPC)7C07D 311/30, A61K 31/35, C07D 407/04, C07D 409/04, C07D 405/04, C07D 413/04, C07D 417/04
(86) International application number:
PCT/JP9905/223
(87) International publication number:
WO 0017/184 (30.03.2000 Gazette 2000/13)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 24.09.1998 JP 27026298

(71) Applicant: MITSUBISHI CHEMICAL CORPORATION
Chiyoda-ku,Tokyo 100-0005 (JP)

(72) Inventors:
  • SHODA, AyaMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • WATANABE, KazutoshiMitsubishi Chem. Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • ARITOMO, KeiichiMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • JIKIHARA, TetsuoMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • ANDO, RyoichiMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • SAITO, Ken-ichiMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • HONDA, ToshiyukiMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)
  • KAWAMOTO, RieMitsubishi Chemical Corporation
    Aoba-kuYokohama-shiKanagawa 227-8502 (JP)

(74) Representative: Sternagel, Fleischer, Godemeyer & PartnerPatentanwälte 
An den Gärten 7
51491 Overath
51491 Overath (DE)

   


(54) HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS