(19)
(11) EP 1 117 407 A1

(12)

(43) Date of publication:
25.07.2001 Bulletin 2001/30

(21) Application number: 99947420.8

(22) Date of filing: 24.09.1999
(51) International Patent Classification (IPC)7A61K 31/537, A61K 47/36
(86) International application number:
PCT/EP9907/117
(87) International publication number:
WO 0018/406 (06.04.2000 Gazette 2000/14)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 28.09.1998 US 102112 P

(71) Applicant: GLAXO GROUP LIMITED
Greenford, Middlesex UB6 ONN (GB)

(72) Inventor:
  • BALIK, Samuel Bruce
    Research Triangle Park, NC 27709 (US)

(74) Representative: Reed, Michael Antony et al
Intellectual Property DepartmentGlaxo Wellcome plcGlaxo Wellcome HouseBerkeley Avenue
Greenford, Middlesex UB6 0NN
Greenford, Middlesex UB6 0NN (GB)

   


(54) ORAL DOSAGE FORMULATIONS COMPRISING (2S, 3S,5R)-2-(3,5-DIFLUOROPHENYL) -3,5-DIMETHYL-2-MORPHOLINOL AND AN EFFECTIVE STABILIZING AMOUNT OF ALGINIC ACID