(19)
(11) EP 1 119 628 A2

(12)

(88) Date of publication A3:
18.01.2001

(43) Date of publication:
01.08.2001 Bulletin 2001/31

(21) Application number: 99953117.1

(22) Date of filing: 11.10.1999
(51) International Patent Classification (IPC)7C12N 15/52, C12N 9/00, C12N 15/63, C12N 5/10, C12P 17/06
(86) International application number:
PCT/US9923/535
(87) International publication number:
WO 0022/139 (20.04.2000 Gazette 2000/16)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 09.10.1998 DE 19846493

(71) Applicant: BRISTOL-MYERS SQUIBB COMPANY
Princeton, NJ 08543-4000 (US)

(72) Inventors:
  • BEYER, Stefan
    D-38124 Braunschweig (DE)
  • BLOECKER, Helmut
    D-38124 Braunschweig (DE)
  • BRANDT, Petra
    D-38124 Braunschweig (DE)
  • CINO, Paul, M.
    Bound Brook, NJ 08805 (US)
  • DOUGHERTY, Brian, A.
    Killingworth, CT 06419 (US)
  • GOLDBERG, Steven, L.
    Basking Ridge, NJ 07920 (US)
  • HOFLE, Gerhard
    D-38124 Braunschweig (DE)
  • MUELLER, Rolf-Joachim
    D-38124 Braunschweig (DE)
  • REICHENBACH, Hans
    D-38124 Braunschweig (DE)

(74) Representative: Kinzebach, Werner, Dr. et al
PatentanwälteReitstötter, Kinzebach und PartnerPostfach 86 06 49
81633 München
81633 München (DE)

   


(54) DNA SEQUENCES FOR ENZYMATIC SYNTHESIS OF POLYKETIDE OR HETEROPOLYKETIDE COMPOUNDS