(19)

(11)

EP 1 121 119 A1

(12)

(43) Date of publication: 08.08.2001 Bulletin 2001/32 (21) Application number: 99951320.3 (22) Date of filing: 13.09.1999

(51) International Patent Classification (IPC)7: A61K 31/35 (86) International application number: PCT/SE9901/598 (87) International publication number: WO 0015/219 (23.03.2000 Gazette 2000/12)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.09.1998 SE 9803157 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventors: EVENDEN, John,AstraZeneca R&D Boston Worcester, MA 01605 (US) THORBERG, Seth-Olov S-151 85 Södertälje (SE)