(19)
(11) EP 1 121 133 A1

(12)

(43) Date of publication:
08.08.2001 Bulletin 2001/32

(21) Application number: 99951948.1

(22) Date of filing: 12.10.1999
(51) International Patent Classification (IPC)7: A61K 31/66, A61K 31/19
(86) International application number:
PCT/US9923/757
(87) International publication number:
WO 0021/542 (20.04.2000 Gazette 2000/16)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.10.1998 US 104374 P
09.11.1998 GB 9824573

(71) Applicants:
  • MERCK & CO., INC.
    Rahway, New Jersey 07065 (US)
  • Merck Frosst Canada & Co.
    Kirkland, Quebec H9H 3L1 (CA)

(72) Inventors:
  • HARADA, Shun-Ichi
    Rahway, NJ 07065 (US)
  • MACHWATE, Mohamed
    Rahway, NJ 07065 (US)
  • RODAN, Gideon, A.
    Rahway, NJ 07065 (US)
  • WEINREB, Miron
    Rahway, NJ 07065 (US)
  • LABELLE, Marc
    Kirkland, Québec H9H 3L1 (CA)
  • METTERS, Kathleen
    Kirkland, Québec H9H 3L1 (CA)
  • YOUNG, Robert, N.
    Kirkland, Québec H9H 3L1 (CA)

(74) Representative: Hiscock, Ian James 
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) METHODS FOR STIMULATING BONE FORMATION