ESTERS OF (+)-ALPHA-( 2,3- DIMETHOXYPHENYL) -1- 2-(4- FLUOROPHENYL) ETHYL]-4- PIPERIDINEMETHANOL AND THEIR USE AS PRODRUGS OF THE 5HT2A RECEPTOR ANTAGONIST MDL 110,907 - Patent 1121345

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EP 1 121 345 A1

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(43)	Date of publication:
	08.08.2001 Bulletin 2001/32

(21)	Application number: 98953458.1

(22)	Date of filing: 14.10.1998

(51)	International Patent Classification (IPC)⁷: C07D 211/22, A61K 31/445

(86)	International application number:
	PCT/US9821/608

(87)	International publication number:
	WO 0021/930 (20.04.2000 Gazette 2000/16)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(71)	Applicant: Aventis Pharmaceuticals Inc.
	Bridgewater, NJ 08807-0800 (US)

(72)	Inventors:
	CARR, Albert, A. Cincinnati, OH 45237 (US) VAN HIJFTE, Luc, E. F-67520 Wangen (FR) KOSLEY, Raymond, W., Jr. Bridgewater, NJ 08807 (US)

(74)	Representative: Wein, Elmar Michael, Dr. et al
	Aventis Pharma Deutschland GmbH,Patent- und Lizenzabteilung,K 801,Industriepark Höchst 65926 Frankfurt am Main 65926 Frankfurt am Main (DE)

(54)	ESTERS OF (+)-ALPHA-( 2,3- DIMETHOXYPHENYL) -1- 2-(4- FLUOROPHENYL) ETHYL]-4- PIPERIDINEMETHANOL AND THEIR USE AS PRODRUGS OF THE 5HT2A RECEPTOR ANTAGONIST MDL 110,907