(19)

(11)

EP 1 124 958 A2

(12)

(88) Date of publication A3: 30.11.2000 (43) Date of publication: 22.08.2001 Bulletin 2001/34 (21) Application number: 99971852.1 (22) Date of filing: 28.10.1999

(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/47, C12N 15/11, C07K 16/18, A61K 38/17 (86) International application number: PCT/US9925/457 (87) International publication number: WO 0028/027 (18.05.2000 Gazette 2000/20)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.11.1998 US 155269 P (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: WALKER, Michael, G. Sunnyvale, CA 94089 (US) VOLKMUTH, Wayne Menlo Park, CA 94025 (US) KLINGLER, Tod, M. San Carlos, CA 94070 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)