(19)
(11) EP 1 127 049 A1

(12)

(43) Date of publication:
29.08.2001 Bulletin 2001/35

(21) Application number: 98963776.4

(22) Date of filing: 03.12.1998
(51) International Patent Classification (IPC)7C07D 207/00
(86) International application number:
PCT/US9825/577
(87) International publication number:
WO 0016/603 (30.03.2000 Gazette 2000/13)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 18.09.1998 US 101077 P
23.09.1998 US 159105

(71) Applicants:
  • GPI NIL Holdings, Inc.
    Wilmington, DE 19899 (US)
  • Amgen Inc.
    Thousand Oaks,California 91320-1799 (US)

(72) Inventors:
  • LI, Jia-He
    Cockeysville, MD 21044 (US)
  • LIMBURG, David
    Baltimore, MD 21234 (US)
  • HAMILTON, Gregory, S.
    Catonsville, MD 21228 (US)
  • STEINER, Joseph, P.
    Hampstead, MD 21074 (US)

(74) Representative: Patentanwälte ,Ruff, Wilhelm, Beier, Dauster & Partner 
Postfach 10 40 36
70035 Stuttgart
70035 Stuttgart (DE)

   


(54) BRIDGED HETEROCYCLIC DERIVATIVES