(19)

(11)

EP 1 127 070 A2

(12)

(88) Date of publication A3: 16.11.2000 (43) Date of publication: 29.08.2001 Bulletin 2001/35 (21) Application number: 99961606.3 (22) Date of filing: 05.11.1999

(51) International Patent Classification (IPC)7: C07K 14/47 (86) International application number: PCT/US9926/274 (87) International publication number: WO 0026/247 (11.05.2000 Gazette 2000/19)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU (30) Priority: 05.11.1998 US 107229 P 27.08.1999 US 151087 P (71) Applicant: Parker Hughes Institute St. Paul, MN 55113 (US)	(72) Inventors: UCKUN, Fatih, M. White Bear Lake, MN 55110 (US) CROTTY, Mya, L. St. Paul, MN 55105 (US) (74) Representative: Nachshen, Neil Jacob et al D Young & Co21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)