(19)

(11)

EP 1 127 277 A1

(12)

(43) Date of publication: 29.08.2001 Bulletin 2001/35 (21) Application number: 99953476.1 (22) Date of filing: 03.11.1999

(51) International Patent Classification (IPC)7: G01N 33/68, G01N 33/577, C12Q 1/68 (86) International application number: PCT/CA9901/038 (87) International publication number: WO 0026/675 (11.05.2000 Gazette 2000/19)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 03.11.1998 CA 2252727 (71) Applicant: McGill University Montreal,Quebec H3A 2A7 (CA)	(72) Inventors: ROULEAU, Guy Montreal,Quebec H3W 2H2 (CA) JOOBER, Ridha Montreal,Quebec H4V 1X6 (CA) (74) Representative: Schlich, George William et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)