(19)
(11) EP 1 128 840 A1

(12)

(43) Date of publication:
05.09.2001 Bulletin 2001/36

(21) Application number: 99955171.6

(22) Date of filing: 27.10.1999
(51) International Patent Classification (IPC)7A61K 38/22, A61P 3/00
(86) International application number:
PCT/US9925/120
(87) International publication number:
WO 0024/418 (04.05.2000 Gazette 2000/18)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.10.1998 US 179461

(71) Applicant: ELI LILLY AND COMPANY
Indianapolis, Indiana 46285 (US)

(72) Inventors:
  • HEIMAN, Mark, L.
    Indianapolis, IN 46250 (US)
  • TINSLEY, Frank, C.
    Indianapolis, IN 46256 (US)
  • CARO, Jose, F.
    Carmel, IN 46033 (US)

(74) Representative: Denholm, Anna Marie 
Eli Lilly and Company Limited,Lilly Research Center,Erl Wood Manor
Windlesham,Surrey GU20 6PH
Windlesham,Surrey GU20 6PH (GB)

   


(54) PREVENTION OF MUSCLE MASS LOSS WITH LEPTIN RECEPTOR LIGANDS