(19)

(11)

EP 1 128 853 A1

(12)

(43) Date of publication: 05.09.2001 Bulletin 2001/36 (21) Application number: 99954190.7 (22) Date of filing: 09.11.1999

(51) International Patent Classification (IPC)7: A61L 27/24, A61L 27/26 (86) International application number: PCT/GB9903/727 (87) International publication number: WO 0027/444 (18.05.2000 Gazette 2000/20)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 09.11.1998 GB 9824562 (71) Applicants: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE 1015 Lausanne (CH) Centre Hospitalier Universitaire Vaudois 1011 Lausanne (CH)	(72) Inventors: HILBORN, Jöns, Gunnar CH-1025 St. Sulpice (CH) FREY, Peter CH-4056 Basel (CH) (74) Representative: Kiddle, Simon John et al Mewburn Ellis,York House,23 Kingsway London WC2B 6HP London WC2B 6HP (GB)