| (19) |
 |
|
(11) |
EP 1 129 709 A3 |
| (12) |
EUROPEAN PATENT APPLICATION |
| (88) |
Date of publication A3: |
|
14.11.2001 Bulletin 2001/46 |
| (43) |
Date of publication A2: |
|
05.09.2001 Bulletin 2001/36 |
| (22) |
Date of filing: 01.03.2001 |
|
|
| (84) |
Designated Contracting States: |
|
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
Designated Extension States: |
|
AL LT LV MK RO SI |
| (30) |
Priority: |
03.03.2000 ES 200000522
|
| (71) |
Applicant: Laboratorio de Aplicaciones Farmacodinamicas, S.A. |
|
08025 Barcelona (ES) |
|
| (72) |
Inventors: |
|
- Tarré Pérez, Maria Teresa
08005 Barcelona (ES)
- Font Faus, Xavier
08021 Barcelona (ES)
- Trullols Casas, Montserrat
08186 Lliica d'Amunt (Barcelona) (ES)
|
| (74) |
Representative: Davila Baz, Angel |
|
c/o Clarke, Modet & Co., Goya, 11
28001 Madrid
28001 Madrid (ES) |
|
| |
|
| (54) |
Pharmaceutical composition based on ibuprofen and a procedure for the preparation
thereof |
(57) Pharmaceutical composition based on ibuprofen and a procedure for the preparation
thereof. The composition, in the form of powder, comprises as active component ibuprofen
lysinate, in combination with cyclodextrin, and other pharmaceutically acceptable
excipients. Its preparation comprises: sieving separately the ibuprofen salt and the
cyclodextrin, mixing these components, submitting the mixture to an ultra-rapid mixing,
and sieving and mixing the resulting mixture along with the excipients.