(19)
(11) EP 1 131 081 A1

(12)

(43) Date of publication:
12.09.2001 Bulletin 2001/37

(21) Application number: 99962741.7

(22) Date of filing: 10.11.1999
(51) International Patent Classification (IPC)7A61K 38/00, A61K 48/00, C07H 21/04, C12N 15/63
(86) International application number:
PCT/US9926/647
(87) International publication number:
WO 0027/416 (18.05.2000 Gazette 2000/20)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 12.11.1998 US 190976

(71) Applicant: Beth Israel Deaconess Medical Center
Boston, MA 02215 (US)

(72) Inventors:
  • SIMONS, Michael
    Chestnut Hill, MA 02167 (US)
  • HOROWITZ, Arie
    Waltham, MA 02154 (US)

(74) Representative: Eyles, Christopher Thomas 
W.P. THOMPSON & CO.Celcon House289-293 High Holborn
London WC1V 7HU
London WC1V 7HU (GB)

   


(54) STIMULATION OF ANGIOGENESIS VIA SYNDECAN-4 CYTOPLASMIC DOMAIN SIGNALING PATHWAY