(19)

(11)

EP 1 131 354 A1

(12)

(43) Date of publication: 12.09.2001 Bulletin 2001/37 (21) Application number: 99960285.7 (22) Date of filing: 12.11.1999

(51) International Patent Classification (IPC)7: C07K 16/00 (86) International application number: PCT/US9926/671 (87) International publication number: WO 0029/443 (25.05.2000 Gazette 2000/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 13.11.1998 US 108325 P (71) Applicant: Euro-Celtique, S.A. 2230 Luxembourg (LU)	(72) Inventors: BURCH, Ronald, M. Wilton, CT 06897 (US) SACKLER, David, A. Greenwich, CT 06830 (US) (74) Representative: Schüssler, Andrea, Dr.  Kanzlei Huber & SchüsslerTruderinger Strasse 246 81825 München 81825 München (DE)