(19)
(11) EP 1 133 312 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
17.10.2007 Bulletin 2007/42

(45) Mention of the grant of the patent:
12.09.2007 Bulletin 2007/37

(21) Application number: 00938173.2

(22) Date of filing: 06.06.2000
(51) International Patent Classification (IPC): 
A61K 38/22(2006.01)
A61P 3/08(2006.01)
A61K 38/26(2006.01)
A61K 31/425(2006.01)
(86) International application number:
PCT/US2000/015548
(87) International publication number:
WO 2000/078333 (28.12.2000 Gazette 2000/52)

(54)

SYNERGISTIC USE OF THIAZOLIDINEDIONES WITH GLUCAGON-LIKE PEPTIDE-1 AND AGONISTS THEREOF TO TREAT NON-INSULIN DEPENDENT DIABETES

SYNERGITISCHE VERWENDUNG VON THIAZOLIDINEDIONEN UND GLUCAGON-ÄHNLICHEM PEPTID-1 UND DESSEN AGONISTEN FÜR DIE BEHANDLUNG VON NICHT-INSULIN-ABHÄNGIGEN DIABETES

UTILISATION COMBINEE DE THIAZOLIDINEDIONES ET DE PEPTIDE-1 DE TYPE GLUCAGONE ET D'AGONISTES DE CES DERNIERS POUR TRAITER DIABETES NON INSULINO-DEPENDANT.


(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 21.06.1999 US 139794 P

(43) Date of publication of application:
19.09.2001 Bulletin 2001/38

(60) Divisional application:
07111988.7

(73) Proprietor: ELI LILLY AND COMPANY
Indianapolis, Indiana 46285 (US)

(72) Inventors:
  • YAKUBU-MADUS, Fatima, Emitsel
    Indianapolis, IN 46256 (US)
  • STRAMM, Lawrence, E.
    Indianapolis, IN 46256 (US)
  • JOHNSON, William, T.
    Indianapolis, IN 46227 (US)
  • VIGNATI, Louis
    Indianapolis, IN 46208 (US)

(74) Representative: Burnside, Ivan John 
Eli Lilly and Company Limited Lilly Research Centre Erl Wood Manor
Windlesham, Surrey GU20 6PH
Windlesham, Surrey GU20 6PH (GB)


(56) References cited: : 
EP-A- 0 733 644
WO-A-98/57636
US-A- 5 631 224
WO-A-00/00195
WO-A-99/03478
   
  • REASNER, C. A., II: "Promising new approaches" DIABETES, OBES. METAB. (1999), 1(SUPPL. 1), S41-S48 , XP000971954
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).