(19)
(11) EP 1 133 521 A1

(12)

(43) Date of publication:
19.09.2001 Bulletin 2001/38

(21) Application number: 99960408.5

(22) Date of filing: 16.11.1999
(51) International Patent Classification (IPC)7: C07K 14/52, A61K 38/19, C07H 21/04
(86) International application number:
PCT/US9927/199
(87) International publication number:
WO 0029/439 (25.05.2000 Gazette 2000/21)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 16.11.1998 US 193092

(71) Applicants:
  • GENETICS INSTITUTE, INC.
    Cambridge,Massachusetts 02140 (US)
  • PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    CambridgeMassachusetts 02138 (US)

(72) Inventors:
  • JACOBS, Kenneth
    Newton, MA 02160 (US)
  • MCCOY, John, M.
    Reading, MA 01867 (US)
  • LAVALLIE, Edward, R.
    Harvard, MA 01451 (US)
  • COLLINS-RACIE, Lisa, A.
    Acton, MA 01720 (US)
  • LU, Zhijian
    Bedford, MA 01730 (US)
  • MI, Sha
    Belmont, MA 02178 (US)
  • KELLEHER, Kerry
    Marlborough, MA 01752 (US)
  • CARLIN-DUCKETT, McKeough
    Belmont, MA 02178 (US)
  • DORF, Martin, E.
    Chesnut Hill, MA 02467 (US)

(74) Representative: Tomlinson, Edward James 
FrohwitterPatent- und RechtsanwältePossartstrasse 20
81679 München
81679 München (DE)

   


(54) THE CXC CHEMOKINE H174 AND METHODS FOR PREVENTING DAMAGE TO THE NERVOUS SYSTEM