(19)
(11) EP 1 135 393 A2

(12)

(88) Date of publication A3:
16.11.2000

(43) Date of publication:
26.09.2001 Bulletin 2001/39

(21) Application number: 99965977.4

(22) Date of filing: 03.12.1999
(51) International Patent Classification (IPC)7C07D 491/048, A61K 31/407, A61P 21/00, A61K 31/403, C07D 209/70, C07D 491/04
(86) International application number:
PCT/US9928/619
(87) International publication number:
WO 0034/285 (15.06.2000 Gazette 2000/24)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 04.12.1998 US 205770

(71) Applicant: AMERICAN HOME PRODUCTS CORPORATION
Madison, New Jersey 07940-0874 (US)

(72) Inventors:
  • ANTANE, Schuyler, A.
    West Windsor, NJ 08550 (US)
  • BUTERA, John, A.
    Clarksburg, NJ 08510 (US)
  • LENNOX, Joseph, R.
    Morrisville, NC 27560 (US)

(74) Representative: Wileman, David Francis, Dr. et al
c/o Wyeth LaboratoriesHuntercombe Lane South
TaplowMaidenheadBerkshire SL6 OPH
TaplowMaidenheadBerkshire SL6 OPH (GB)

   


(54) SUBSTITUTED BENZOFURANOINDOLES AND INDENOINDOLES AS NOVEL POTASSIUM CHANNEL OPENERS