(19)
(11) EP 1 135 518 A1

(12)

(43) Date of publication:
26.09.2001 Bulletin 2001/39

(21) Application number: 99958952.6

(22) Date of filing: 12.11.1999
(51) International Patent Classification (IPC)7C12P 21/00, A01K 67/00, C07H 21/02, C07H 21/04, C12N 15/00
(86) International application number:
PCT/US9926/870
(87) International publication number:
WO 0029/608 (25.05.2000 Gazette 2000/21)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 13.11.1998 US 108195 P
09.07.1999 US 142925 P

(71) Applicant: NEW YORK UNIVERSITY
New York, NY 10012 (US)

(72) Inventors:
  • WU, Xue-Ru
    Woodside, NY 11377-2148 (US)
  • SUN, Tung-Tien
    Scarsdale, NY 10583 (US)

(74) Representative: Halldin, Bo et al
Dr. Ludwig Brann Patentbyra ABP.O. Box 17192
104 62 Stockholm
104 62 Stockholm (SE)

   


(54) TRANSGENIC ANIMALS AS URINARY BIOREACTORS FOR THE PRODUCTION OF PROTEIN IN THE URINE, RECOMBINANT DNA CONSTRUCT FOR KIDNEY-SPECIFIC EXPRESSION, AND METHOD OF USING SAME