(19)

(11)

EP 1 137 402 A1

(12)

(43) Date of publication: 04.10.2001 Bulletin 2001/40 (21) Application number: 99961183.3 (22) Date of filing: 08.12.1999

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 47/24 (86) International application number: PCT/GB9904/070 (87) International publication number: WO 0033/817 (15.06.2000 Gazette 2000/24)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 08.12.1998 GB 9827006 27.10.1999 GB 9925365 (71) Applicant: PHARES PHARMACEUTICAL RESEARCH N.V. CuracaoNetherlands Antilles (AN)	(72) Inventors: LEIGH, Steven Kriegackerstrasse 304132 Muttenz (CH) LEIGH, Mathew, Louis, Steven Kriegackerstrasse 304132 Muttenz (CH) (74) Representative: Schreiber, Wolfgang F. et al Riederer Hasler & PartnerPatentanwälte AGElestastrasse 8 7310 Bad Ragaz 7310 Bad Ragaz (CH)