EFFICIENT AND STABLE $I(IN VIVO) GENE TRANSFER TO CARDIOMYOCYTES USING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS - Patent 1139751

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EP 1 139 751 A1

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(43)	Date of publication:
	10.10.2001 Bulletin 2001/41

(21)	Application number: 99967703.2

(22)	Date of filing: 28.12.1999

(51)	International Patent Classification (IPC)⁷: A01N 43/04, A61K 31/70, C12N 15/00, C12N 15/63

(86)	International application number:
	PCT/US9931/093

(87)	International publication number:
	WO 0038/518 (06.07.2000 Gazette 2000/27)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

28.12.1998 US 113923 P

(71)	Applicant: Arch Development Corporation
	Chicago, IL 60637 (US)

(72)	Inventors:
	LEIDEN, Jeffrey, M.Harvard Medical School Boston, MA 02115 (US) SVENSSON, EricUniversity of Chicago Chicago, IL 60637 (US)

(74)	Representative: Lock, Graham James et al
	Fry Heath & Spence,The Old College,53 High Street Horley,Surrey RH6 7BN Horley,Surrey RH6 7BN (GB)

(54)	EFFICIENT AND STABLE $I(IN VIVO) GENE TRANSFER TO CARDIOMYOCYTES USING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS