(19)
(11) EP 1 139 972 A1

(12)

(43) Date of publication:
10.10.2001 Bulletin 2001/41

(21) Application number: 99967609.1

(22) Date of filing: 23.12.1999
(51) International Patent Classification (IPC)7A61K 6/00
(86) International application number:
PCT/US9930/868
(87) International publication number:
WO 0037/026 (29.06.2000 Gazette 2000/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 23.12.1998 US 221668
23.12.1998 US 113612 P

(71) Applicants:
  • SYNAPTIC PHARMACEUTICAL CORPORATION
    Paramus,New Jersey 07652-1410 (US)
  • MERCK & CO., INC.
    Rahway, New Jersey 07065 (US)

(72) Inventors:
  • CUI, Donghui
    Newtown, PA 18940 (US)
  • DAVIS, Margaret, R.
    Redmond, WA 98053 (US)
  • KARI, Hanumath, P.
    Hatfield, PA 19440 (US)
  • VYAS, Kamlesh, P.
    North Wales, PA 19454 (US)
  • ZHANG, Kanyin
    San Diego, CA 92129 (US)
  • EVANS, Benjamin
    Lansdale, PA 19446 (US)
  • DUNN, Michael
    Cambridge, MA 02138 (US)
  • NAGARATHNAM, Dhanapalan
    Ramsey, NJ 07446 (US)
  • LAGU, Bharat
    Maywood, NJ 07607 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) DIHYDROPYRIMIDINES AND USES THEREOF