(19)
(11)
EP 1 140 046 A1
(12)
(43)
Date of publication:
10.10.2001
Bulletin 2001/41
(21)
Application number:
99966203.4
(22)
Date of filing:
14.12.1999
(51)
International Patent Classification (IPC)
7
:
A61K
31/00
,
A61K
31/196
,
A61K
31/166
,
A61K
31/136
,
A61K
31/41
,
A61K
31/495
,
A61K
31/4453
,
A61K
31/40
,
A61K
31/4465
,
A61K
31/5375
,
A61K
31/381
,
A61K
31/341
,
A61K
31/18
,
A61P
37/06
(86)
International application number:
PCT/US9929/591
(87)
International publication number:
WO 0035/435
(
22.06.2000
Gazette 2000/25)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
15.12.1998
US 112369 P
(71)
Applicant:
WARNER-LAMBERT COMPANY
Morris PlainsNew Jersey 07950 (US)
(72)
Inventor:
GILBERTSEN, Richard, Buell
Ann Arbor, MI 48103 (US)
(74)
Representative:
Mansmann, Ivo et al
Warner-Lambert Company,Patent Department,c/o Gödecke GmbH
79090 Freiburg
79090 Freiburg (DE)
(54)
USE OF A MEK INHIBITOR FOR PREVENTING TRANSPLANT REJECTION