(19)

(11)

EP 1 140 101 A1

(12)

(43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 99966449.3 (22) Date of filing: 17.12.1999

(51) International Patent Classification (IPC)7: A61K 31/53, A61P 33/02 (86) International application number: PCT/US9930/284 (87) International publication number: WO 0037/084 (29.06.2000 Gazette 2000/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 22.12.1998 US 218712 (71) Applicant: Bayer Corporation Pittsburgh, PA 15205-9741 (US)	(72) Inventor: KENNEDY, Thomas, J. Mission, KS 66202 (US) (74) Representative: Krieg, Robert Alexander  Bayer AG,Konzernbereich RP,Patente und Lizenzen 51368 Leverkusen 51368 Leverkusen (DE)