(19)

(11)

EP 1 140 143 A2

(12)

(88) Date of publication A3: 14.09.2000 (43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 99965894.1 (22) Date of filing: 16.12.1999

(51) International Patent Classification (IPC)7: A61K 38/21, A61K 31/7056, A61P 31/14 (86) International application number: PCT/US9927/935 (87) International publication number: WO 0037/110 (29.06.2000 Gazette 2000/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 18.12.1998 US 215876 (71) Applicant: SCHERING CORPORATION KenilworthNew Jersey 07033 (US)	(72) Inventors: GLUE, Paul, W. Flemington, NJ 08822 (US) ALBRECHT, Janice, K. Winter Park, FL 32789 (US) (74) Representative: Ritter, Stephen David et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)