(19)
(11) EP 1 140 966 A1

(12)

(43) Date of publication:
10.10.2001 Bulletin 2001/41

(21) Application number: 99966442.8

(22) Date of filing: 16.12.1999
(51) International Patent Classification (IPC)7C07H 21/00, A61K 31/70
(86) International application number:
PCT/US9930/266
(87) International publication number:
WO 0040/592 (13.07.2000 Gazette 2000/28)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 30.12.1998 US 223498
19.07.1999 US 356069

(71) Applicant: Oligos Etc. Inc.
Wilsonville, OR 97070 (US)

(72) Inventors:
  • DALE, Roderic, M., K.
    Wilsonville, OR 97070 (US)
  • GATTON, Steven, L.
    Lake Oswego, OR 97035-8130 (US)
  • ARROW, Amy
    Bethel, ME 04217 (US)

(74) Representative: Viering, Jentschura & Partner 
Postfach 22 14 43
80504 München
80504 München (DE)

   


(54) ACID STABLE BACKBONE MODIFIED END-BLOCKED NUCLEIC ACIDS AND THERAPEUTIC USES THEREOF