(19)

(11)

EP 1 141 000 A1

(12)

(43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 99962603.9 (22) Date of filing: 24.12.1999

(51) International Patent Classification (IPC)7: C07K 14/315, C07K 16/12, C07H 19/00, C12N 1/20, C12Q 1/68, A61K 35/74, A61K 39/09 (86) International application number: PCT/NZ9900/228 (87) International publication number: WO 0039/159 (06.07.2000 Gazette 2000/27)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.12.1998 NZ 33358998 (71) Applicant: AUCKLAND UNISERVICES LIMITED Auckland (NZ)	(72) Inventors: FRASER, John David,Auckland UniServices Limited Auckland (NZ) PROFT, ThomasAuckland UniServices Limited Auckland (NZ) (74) Representative: Chapman, Paul William et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)