(19)
(11) EP 1 141 280 A1

(12)

(43) Date of publication:
10.10.2001 Bulletin 2001/41

(21) Application number: 00902202.1

(22) Date of filing: 17.01.2000
(51) International Patent Classification (IPC)7C12N 15/12, C07K 14/705, C12N 15/86, C12N 5/10, A61K 39/00, A61K 31/70, C12N 5/08, A61K 35/14, C07K 16/28, G01N 33/574, G01N 33/577, A61K 39/395, C12Q 1/68, A61P 35/00
(86) International application number:
PCT/NL0000/029
(87) International publication number:
WO 0042/181 (20.07.2000 Gazette 2000/29)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 15.01.1999 EP 99200112

(71) Applicant: Crucell Holland B.V.
2333 CN Leiden (NL)

(72) Inventors:
  • DOLSTRA, Harmen
    NL-6605 XL Wychen (NL)
  • VERLINDEN, Stefan, Frederik, Franciscus
    NL-2312 WB Leiden (NL)
  • VAN DE WIEL - VAN KEMENADE, Petronella
    NL-3733 BP Bilthoven (NL)

(74) Representative: Prins, Adrianus Willem et al
Vereenigde,Nieuwe Parklaan 97
2587 BN Den Haag
2587 BN Den Haag (NL)

   


(54) MINOR HISTOCOMPATIBILITY ANTIGENS AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF TUMORS