(19)

(11)

EP 1 141 323 A1

(12)

(43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 98964774.8 (22) Date of filing: 18.12.1998

(51) International Patent Classification (IPC)7: C12N 15/54, C12N 9/10, C12N 15/09, C12Q 1/48 (86) International application number: PCT/US9826/923 (87) International publication number: WO 0037/655 (29.06.2000 Gazette 2000/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: CELL THERAPEUTICS, INC. Seattle, WA 98119 (US)	(72) Inventors: LEUNG, David, W. Mercer Island, WA 98040 (US) ARDOUREL, Daniel Woodinville, WA 98072 (US) HOLLENBACK, David Seattle, WA 98107 (US) (74) Representative: Plougmann, Vingtoft & Partners A/S  Sankt Annae Plads 11,P.O. Box 3007 1021 Copenhagen K 1021 Copenhagen K (DK)