(19)

(11)

EP 1 141 380 A1

(12)

(43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 99961211.2 (22) Date of filing: 15.12.1999

(51) International Patent Classification (IPC)7: C12Q 1/04, C12Q 1/54, C12M 1/30, B01L 3/00 (86) International application number: PCT/GB9904/244 (87) International publication number: WO 0036/139 (22.06.2000 Gazette 2000/25)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.12.1998 GB 9827584 (71) Applicant: CELSIS INTERNATIONAL PLC Cambridge CB4 4FX (GB)	(72) Inventors: GRANT, Peter, Leonard NeedingworthCambs. PE17 3UE (GB) PIRZAD, Ramin St. IvesCambs. PE17 6NL (GB) (74) Representative: Perry, Robert Edward et al GILL JENNINGS & EVERYBroadgate House7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)