(19)

(11)

EP 1 141 724 A1

(12)

(43) Date of publication: 10.10.2001 Bulletin 2001/41 (21) Application number: 99963638.4 (22) Date of filing: 23.12.1999

(51) International Patent Classification (IPC)7: G01N 33/58, C12Q 1/68, G01R 33/465 (86) International application number: PCT/GB9904/395 (87) International publication number: WO 0040/972 (13.07.2000 Gazette 2000/28)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 30.12.1998 GB 9828853 (71) Applicant: NYCOMED AMERSHAM PLC AmershamBuckinghamshire, HP7 9LL (GB)	(72) Inventors: KNOX, Peter Chalfont St. Giles,Bucks HP8 4HS (GB) COOK, Neil Tutshill,Chepstow NP6 7EG (GB)