PHARMACEUTICAL COMPOSITION AND USE OF RNSAID FOR TREATING INFLAMMATION

(19)

(11)

EP 1 143 958 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	23.05.2007 Bulletin 2007/21

(45)	Mention of the grant of the patent:
	31.01.2007 Bulletin 2007/05

(21)	Application number: 99968626.4

(22)	Date of filing: 03.09.1999

(51)

International Patent Classification (IPC):

A61K 31/00^(2006.01)

(86)	International application number:
	PCT/US1999/020261

(87)	International publication number:
	WO 2000/013684 (16.03.2000 Gazette 2000/11)

(54)	PHARMACEUTICAL COMPOSITION AND USE OF RNSAID FOR TREATING INFLAMMATION PHARMAZEUTISCHE ZUSAMMENSETZUNG UND VERWENDUNG VON RNSAID ZUR BEHANDLUNG DER ENTZÜNDUNG COMPOSITION PHARMACEUTIQUE ET PROCEDE DE TRAITEMENT DES INFLAMMATIONS AVEC DES DAINSR

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30)

Priority:

03.09.1998 US 146395

(43)	Date of publication of application:
	17.10.2001 Bulletin 2001/42

(73)	Proprietor: LOMA LINDA UNIVERSITY MEDICAL CENTER
	Loma Linda, California 92354 (US)

(72)	Inventor:
	WECHTER, William, J. Ojai, CA 93023 (US)

(74)	Representative: Dzieglewska, Hanna Eva
	Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)

(56)

References cited: :

EP-A- 0 935 961
WO-A-98/09603
US-A- 5 331 000

WO-A-94/28890
US-A- 5 200 198

GHEZZI: "differential contribution of R and S isomers in ketoprofen anti-inflammatory activity:..." JOURNAL OF PHARMACOLOGYAND EXPERIMENTAL THERAPEUTICS, vol. 287, no. 3, 1998, pages 969-973, XP000874029
BRUNE: "aspirine-like drugs may block pain independently..." EXPERIMENTIA, vol. 47, no. 3, 1991, pages 257-261, XP000874947
ADAMS: "pharmacological differences between the optical isomers..." J. PHARMACY AND PHARMACOLOGY, vol. 28, 1976, pages 256-257, XP000874955
JAMALI: "pharmacokinetics of enantiomers of chiral non-steroidal..." DRUG METABOLISM, vol. 13, - 1988 pages 1-9, XP000874176
SUESA N ET AL: "Stereoselective cyclooxygenase inhibition in cellular models by the enantiomers of ketoprofen." CHIRALITY, (1993) 5 (8) 589-95., XP000874055


	Remarks:
	WIPO A3 publication data is not currently available.

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).