(19)
(11) EP 1 144 012 A1

(12)

(43) Date of publication:
17.10.2001 Bulletin 2001/42

(21) Application number: 00904440.5

(22) Date of filing: 21.01.2000
(51) International Patent Classification (IPC)7A61K 47/48, A61P 35/00
(86) International application number:
PCT/US0001/346
(87) International publication number:
WO 0043/043 (27.07.2000 Gazette 2000/30)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 21.01.1999 US 116792 P

(71) Applicant: GEORGETOWN UNIVERSITY
Washington, D.C. 20057 (US)

(72) Inventors:
  • XU, Liang
    Arlington, VA 22209 (US)
  • CHANG, Esther, H.
    Chevy Chase, MD 20815 (US)

(74) Representative: Daniels, Jeffrey Nicholas et al
Page White & Farrer54 Doughty Street
London WC1N 2LS
London WC1N 2LS (GB)

   


(54) LIGAND-PEG POST-COATING STABILIZED LIPOPLEX AND POLYPLEX FOR TARGETED GENE DELIVERY