4-ARYLAMINO, 4-ARYLOXY, AND 4-ARYLTHIO DIARYLAMINES AND DERIVATIVES THEREOF AS SELECTIVE MEK INHIBITORS - Patent 1144362

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EP 1 144 362 A1

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(43)	Date of publication:
	17.10.2001 Bulletin 2001/42

(21)	Application number: 99968152.1

(22)	Date of filing: 21.12.1999

(51)	International Patent Classification (IPC)⁷: C07C 229/58, C07C 321/30, C07D 213/60, A61K 31/10, A61K 31/185, A61K 31/21, A61K 31/325, A61K 31/44, A61P 35/00

(86)	International application number:
	PCT/US9930/418

(87)	International publication number:
	WO 0041/994 (20.07.2000 Gazette 2000/29)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

13.01.1999 US 115670 P
02.03.1999 US 122421 P

(71)	Applicant: WARNER-LAMBERT COMPANY
	Morris PlainsNew Jersey 07950 (US)

(72)	Inventors:
	BARRETT, Stephen, Douglas Livonia, MI 48154 (US) TECLE, Haile Ann Arbor, MI 48108 (US)

(74)	Representative: Mansmann, Ivo et al
	Warner-Lambert Company,Patent Department,c/o Gödecke GmbH 79090 Freiburg 79090 Freiburg (DE)

(54)	4-ARYLAMINO, 4-ARYLOXY, AND 4-ARYLTHIO DIARYLAMINES AND DERIVATIVES THEREOF AS SELECTIVE MEK INHIBITORS