(19)

(11)

EP 1 144 619 A1

(12)

(43) Date of publication: 17.10.2001 Bulletin 2001/42 (21) Application number: 00928724.4 (22) Date of filing: 02.05.2000

(51) International Patent Classification (IPC)7: C12N 15/10, C07K 1/34, B01D 61/14 (86) International application number: PCT/US0011/926 (87) International publication number: WO 0066/723 (09.11.2000 Gazette 2000/45)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 04.05.1999 US 132369 P 14.02.2000 US 182357 P (71) Applicant: MILLIPORE CORPORATION BedfordMassachusetts 01730 (US)	(72) Inventor: LEONARD, Jack, T. South Hamilton, MA 01982 (US) (74) Representative: Greenwood, John David et al Graham Watt & Co.Riverhead SevenoaksKent TN13 2BN SevenoaksKent TN13 2BN (GB)