(19)

(11)

EP 1 144 638 A2

(12)

(43) Date of publication: 17.10.2001 Bulletin 2001/42 (21) Application number: 99931394.3 (22) Date of filing: 27.07.1999

(51) International Patent Classification (IPC)7: C12N 15/31, C12N 15/62, C07K 14/295, C07K 16/12, C12Q 1/68, G01N 33/53, G01N 33/543, G01N 33/569, A61K 39/02, A61K 48/00 (86) International application number: PCT/IB9901/328 (87) International publication number: WO 0006/739 (10.02.2000 Gazette 2000/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 27.07.1998 US 94198 P 26.07.1999 US 360707 (71) Applicant: Aventis Pasteur Limited Toronto,Ontario M2R 3T4 (CA)	(72) Inventors: MURDIN, Andrew, D. Newmarket, Ontario L3X 1V2 (CA) OOMEN, Raymond, P. Schomberg, Ontario L0G 1T0 (CA) (74) Representative: MacLean, Martin Robert et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)
	Remarks: WIPO A3 publication data is not currently available.