(19)

(11)

EP 1 144 654 A3

(12)

(88) Date of publication A3: 11.10.2001 (43) Date of publication A2: 17.10.2001 Bulletin 2001/42 (21) Application number: 00962730.8 (22) Date of filing: 25.09.2000

(51) International Patent Classification (IPC)7: C12N 15/57, C12N 9/64, C12N 5/10, C12N 15/63, C12P 21/02, C07K 16/40, A61K 38/43, C12Q 1/68, G01N 33/573 (86) International application number: PCT/GB0003/680 (87) International publication number: WO 0123/587 (05.04.2001 Gazette 2001/14)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 25.09.1999 GB 9922835 (71) Applicant: SMITHKLINE BEECHAM PLC Brentford, Middlesex TW8 9EP (GB)	(72) Inventor: SOUTHAN, Christopher, D.,SmithKline Beecham Pharm Harlow,Essex CM19 5AW (GB) (74) Representative: Crump, Julian Richard John  FJ Cleveland, 40-43 Chancery Lane London WC2A 1JQ London WC2A 1JQ (GB)
	Remarks: WIPO A3 publication data is not currently available.